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C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP), which your body produces in response to inflammation. It helps doctors assess whether you have low-grade inflammation that might be affecting your health.

Quick summary

["CRP helps track subtle inflammation, often used to monitor conditions like heart disease risk or infection response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32706-4
Short code
N men sg A+C+W135+Y Ag Ur Ql
Synonyms
N men sg A+C+W135+Y Ag Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why CRP Matters in Health

CRP is a marker for inflammation, a natural response to injury, infection, or illness. While CRP levels rise with acute infections (like pneumonia), they can also signal chronic inflammation that may contribute to conditions like heart disease, arthritis, or metabolic disorders. High levels may prompt further evaluation to understand underlying causes.

When This Test Is Ordered

Your doctor might order a high-sensitivity CRP test to monitor long-term inflammation, check for signs of heart disease risk, evaluate autoimmune conditions, or assess response to treatments. It’s often used alongside other tests, such as cholesterol or blood sugar levels.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm or vein to draw blood. If you’re concerned about needles, let your healthcare provider know—they can offer alternatives.

What the Results Mean

Results are reported in milligrams per liter (mg/L). While reference ranges vary by lab, higher-than-normal levels may indicate inflammation, while very low levels might suggest reduced immune response. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP’s Role in Diagnosis and Management

Short name

CRP (High-Sensitivity)

Frequently asked questions

How does CRP help doctors diagnose conditions?
CRP is particularly useful for detecting low-grade inflammation that isn’t obvious through other tests. For example, it can help identify early signs of cardiovascular disease, autoimmune disorders, or chronic infections. Doctors may use it to guide treatment decisions, such as adjusting medications for conditions like rheumatoid arthritis or monitoring recovery from surgery.
Can CRP levels change with diet or lifestyle?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a heart-healthy diet, managing weight, and reducing smoking or alcohol may help lower CRP and reduce inflammation over time.
What if my CRP levels are consistently high?
If your CRP levels remain elevated, your doctor may recommend further testing or lifestyle changes to address potential causes. This could include investigating infections, autoimmune conditions, or other health concerns that require medical evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy