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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check: creatinine levels help determine if your kidneys are working properly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108995-2
Short code
N men sg A IgG Msmt Ser
Synonyms
N men sg A IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Your Kidneys Matter

Your kidneys filter waste and extra substances from your blood, including creatinine. If your kidneys aren’t working well, creatinine levels in your blood may rise. This test is often used to monitor kidney health, especially in people with conditions like diabetes, high blood pressure, or a family history of kidney disease.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader kidney function panel. Bring any medications you’re taking, as some may affect results.

What the Results Mean

Higher than expected levels may suggest kidney problems, while lower levels could indicate dehydration or muscle breakdown. Your doctor will interpret results in relation to your overall health and medical history.

Common Causes of Abnormal Results

Creatinine levels can be affected by factors like dehydration, muscle mass, or certain medications. Chronic kidney disease, kidney stones, or heart failure are conditions that may lead to elevated levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing and managing kidney disease, guiding treatment decisions, and monitoring progression of conditions that impact kidney function. It’s also used to assess kidney function before surgeries or procedures.

Short name

Creatinine Level

Frequently asked questions

Why might my creatinine level be checked regularly?
Your doctor may order this test if you have symptoms like swelling, fatigue, or frequent urination, or if you have a condition that increases kidney risk (e.g., diabetes or high blood pressure). It’s also part of routine check-ups for people at higher risk.
Could my diet affect this test?
Eating foods high in protein or muscle-building supplements may temporarily raise creatinine levels. Avoiding excessive protein intake for a day or two before testing can help stabilize results.
What if my results are out of the normal range?
Your doctor will discuss your results with you and may recommend further tests or adjustments to your treatment plan. Follow-up may include additional kidney function tests or lifestyle recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy