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Urine Albumin-to-Creatinine Ratio (ACR)

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of albumin (a protein) to creatinine (a waste product from muscle) in your urine. It helps assess how much protein is leaking into your urine, which can indicate kidney damage or other kidney-related conditions.

Quick summary

["Helps detect early kidney problems by checking for protein loss in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17321-1
Short code
N men sg A+Y Ag Ur Ql
Synonyms
N men sg A+Y Ag Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Kidneys normally filter waste and extra fluid from your blood. If they’re damaged, they may allow small amounts of protein (like albumin) to appear in urine. This test helps identify early signs of kidney issues, such as diabetic nephropathy or glomerulonephritis, before symptoms become severe.

How the Test Works

A small urine sample is collected (often during a 24-hour period or a single random sample). The lab measures albumin and creatinine levels separately and calculates their ratio. Higher ratios may signal kidney problems, while normal ratios suggest healthy kidney function.

What to Expect Before the Test

No special preparation is needed unless instructed by your doctor. You may be asked to collect urine over 24 hours (morning to morning) or provide a single random sample. Avoid certain medications or foods that could affect results (e.g., high-protein diets or certain supplements).

Possible Results and Next Steps

Results are typically reported as a ratio (e.g., mg/mmol). A high ratio may prompt further kidney tests, like blood tests or imaging. A normal ratio doesn’t guarantee kidney health, so follow-up may still be needed if you have risk factors (e.g., diabetes, high blood pressure).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Urine Albumin:Creatinine Ratio

Frequently asked questions

What does a high urine albumin-to-creatinine ratio mean?
A high ratio suggests **microalbuminuria**, a mild form of kidney damage where small amounts of protein leak into urine. This is often seen in conditions like diabetes or high blood pressure. Your doctor may recommend lifestyle changes (e.g., blood pressure control, diet) or additional tests to monitor kidney health.
What if my ratio is normal?
A normal ratio means your kidneys are likely filtering waste properly, but it doesn’t rule out all kidney risks. If you have diabetes, high blood pressure, or other health conditions, your doctor may still monitor you closely with follow-up tests or lifestyle advice.
Can diet affect this test?
Yes. High-protein diets or certain medications (e.g., NSAIDs like ibuprofen) can temporarily increase albumin in urine. Avoid these unless approved by your doctor. Stick to a standard diet for 24 hours before testing to get accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy