Urine Albumin-to-Creatinine Ratio (ACR)
This test measures the ratio of albumin (a protein) to creatinine (a waste product from muscle) in your urine. It helps assess how much protein is leaking into your urine, which can indicate kidney damage or other kidney-related conditions.
["Helps detect early kidney problems by checking for protein loss in urine."]
Key facts at a glance
- LOINC
- 17321-1
- Short code
- N men sg A+Y Ag Ur Ql
- Synonyms
- N men sg A+Y Ag Ur Ql
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Kidneys normally filter waste and extra fluid from your blood. If they’re damaged, they may allow small amounts of protein (like albumin) to appear in urine. This test helps identify early signs of kidney issues, such as diabetic nephropathy or glomerulonephritis, before symptoms become severe.
How the Test Works
A small urine sample is collected (often during a 24-hour period or a single random sample). The lab measures albumin and creatinine levels separately and calculates their ratio. Higher ratios may signal kidney problems, while normal ratios suggest healthy kidney function.
What to Expect Before the Test
No special preparation is needed unless instructed by your doctor. You may be asked to collect urine over 24 hours (morning to morning) or provide a single random sample. Avoid certain medications or foods that could affect results (e.g., high-protein diets or certain supplements).
Possible Results and Next Steps
Results are typically reported as a ratio (e.g., mg/mmol). A high ratio may prompt further kidney tests, like blood tests or imaging. A normal ratio doesn’t guarantee kidney health, so follow-up may still be needed if you have risk factors (e.g., diabetes, high blood pressure).
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Urine Albumin:Creatinine Ratio
Frequently asked questions
What does a high urine albumin-to-creatinine ratio mean?
What if my ratio is normal?
Can diet affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy