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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when your body breaks down old red blood cells.

Quick summary

["Bilirubin helps your liver process waste and keeps your skin and eyes from turning yellow."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32707-2
Short code
N men sg B+E coli K1 Ag Ur Ql
Synonyms
N men sg B+E coli K1 Ag Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to check for liver disease, bile duct blockages, or conditions that affect how your body breaks down red blood cells. It can also help diagnose jaundice (yellowing of the skin and eyes) or monitor treatment for conditions like hemolytic anemia or liver disorders.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know—they can help make the process more comfortable.

What the Results Mean

Higher than normal levels may suggest liver problems, gallbladder issues, or red blood cell disorders. Lower levels might indicate liver disease or certain medications affecting bilirubin processing. Your doctor will interpret results in the context of your overall health.

Common Conditions Monitored

This test is often used to monitor conditions like hepatitis, cirrhosis, or bile duct obstructions. It can also help track how well your body is processing bilirubin after treatments for blood disorders or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Bilirubin Levels and Health

Short name

Total Serum Bilirubin

Frequently asked questions

What causes elevated bilirubin levels?
Elevated bilirubin can result from liver disease, blocked bile ducts, or conditions that destroy red blood cells faster than the liver can process it. Symptoms like jaundice (yellow skin/eyes) may appear with high levels.
How often should I get this test?
Frequency depends on your health condition. If you have liver disease, your doctor may recommend regular monitoring. If you’re asymptomatic, tests may be done only if symptoms or risk factors (like family history) suggest it.
Can diet affect bilirubin levels?
Dietary changes alone won’t alter bilirubin levels, but certain foods (like excessive alcohol or high-fat meals) may affect liver function indirectly. Stick to your doctor’s advice for managing any underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy