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Serum or plasma concentration of bile acids (total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bile acids in your blood, which helps assess liver function and bile flow.

Quick summary

["Bile acids support digestion and may indicate liver or gallbladder issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33401-1
Short code
N men sg B+E coli K1 Ag Ur Ql LA
Synonyms
N men sg B+E coli K1 Ag Ur Ql LA
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
la
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Bile Acid Testing Used For?

Bile acids are produced by the liver and stored in the gallbladder. When released into the small intestine, they help break down fats. Elevated levels in the blood can signal problems like liver disease, bile duct blockages, or certain metabolic disorders. Your doctor may order this test if you have symptoms like jaundice, unexplained fatigue, or digestive issues.

Why Might Your Doctor Request This Test?

Common reasons include investigating unexplained jaundice, assessing liver function in chronic liver diseases, or diagnosing conditions like primary biliary cholangitis or cystic fibrosis. It may also be used in research or specialized clinical settings.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then processed to measure the total bile acid concentration in serum or plasma. Results are typically reported as a concentration value.

What Do Results Mean?

Higher-than-normal levels may indicate liver disease, bile duct obstruction, or other metabolic conditions. Lower-than-normal levels might suggest bile acid malabsorption or certain genetic disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated bile acids can reflect impaired liver function, gallbladder disease, or bile duct issues. They may also be elevated in conditions like cirrhosis, hepatitis, or pancreatic cancer. Low levels can be associated with conditions like Whipple’s disease or certain genetic disorders affecting bile acid metabolism. Always discuss results with your healthcare provider.

Short name

Total Bile Acids

Frequently asked questions

How long does it take to get results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Some labs may provide preliminary results sooner, but final interpretations require clinical correlation.
Can diet or medications affect bile acid test results?
Yes, certain foods (like high-fat meals) and medications (e.g., bile acid sequestrants) can temporarily influence bile acid levels. Your doctor may advise fasting or timing your test around specific dietary or medication schedules to ensure accurate results.
Is this test painful or uncomfortable?
The blood draw itself is generally mild discomfort, similar to a routine lab test. Most people tolerate it well, and any minor bruising or soreness fades quickly. If you have a hard-to-reach vein or are anxious, your doctor may use a different approach.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy