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Neutrophil-to-Lymphocyte Ratio (NLR) in Whole Blood by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of neutrophils to lymphocytes in your blood, which can help assess immune response and inflammation.

Quick summary

["Neutrophils and lymphocytes are key white blood cells; their balance may signal health or disease states."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86236-7
Short code
N men sg C synE Ct Spec Qn NAA+probe
Synonyms
N men sg C synE Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is the Purpose of This Test?

Doctors may order this test to evaluate immune function, inflammation, or response to infections, cancers, or other conditions affecting these cells. It’s often used alongside other blood tests to guide treatment decisions.

How Is the Sample Collected?

A small blood sample is drawn from a vein, usually in your arm. The blood is processed to separate the white blood cells for analysis.

What Does the Result Mean?

A higher ratio may suggest infection, inflammation, or certain cancers, while a lower ratio could indicate immune suppression or other conditions. Your doctor will interpret results in the context of your overall health and symptoms.

Common Reasons for Testing

This test is commonly used in monitoring chronic diseases (e.g., cancer, autoimmune disorders), evaluating infections, or assessing post-surgery recovery. It may also help guide decisions about medications that affect white blood cells.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Neutrophils and lymphocytes play distinct roles in the immune system. Neutrophils are the body’s first responders to infections, while lymphocytes help fight chronic infections and cancers. An elevated ratio may signal acute inflammation or infection, while a suppressed ratio could indicate conditions like leukemia, HIV, or certain immune deficiencies. Doctors use these findings to tailor treatments, such as adjusting chemotherapy or antibiotic therapy.

Short name

NLR (Whole Blood)

Frequently asked questions

Why might my doctor request this test?
Your doctor may order this test if you have symptoms like fever, fatigue, or unexplained weight loss, or if you’re undergoing treatment for conditions like cancer, autoimmune diseases, or infections. It can also be part of routine monitoring for certain chronic illnesses.
What are typical reference ranges?
Reference ranges vary by lab and individual health. A higher or lower ratio than expected may prompt further testing or evaluation of your overall health.
Can I eat or drink before this test?
No special preparation is needed for this test. However, always follow your doctor’s instructions regarding fasting or other restrictions if applicable to your test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy