C-reactive protein (CRP) by nephelometry (serum/plasma)
This test measures a protein called C-reactive protein (CRP), which your body produces in response to inflammation. CRP helps doctors assess whether you have an inflammatory condition, infection, or other health issues that cause swelling in your body.
["CRP helps track inflammation, guiding treatment decisions and monitoring conditions like infections or autoimmune diseases."]
Key facts at a glance
- LOINC
- 17325-2
- Short code
- N men sg C+W135 Ag Ur Ql
- Synonyms
- N men sg C+W135 Ag Ur Ql
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why CRP Matters in Your Health
CRP is often used as a simple blood test to detect inflammation, which can signal underlying health problems. High levels may indicate conditions such as infections, autoimmune diseases (like rheumatoid arthritis), or other inflammatory processes. Doctors may order this test to monitor chronic conditions or check for signs of new health concerns.
How the Test Works
Your blood sample is analyzed using a nephelometric method, which measures how much CRP is present in your serum or plasma. This test is highly sensitive and can detect even small amounts of CRP, making it useful for early detection of inflammation.
What to Expect Before the Test
No special preparation is usually needed for this test. You may be asked to fast for 8–12 hours before the blood draw if your doctor specifies it, but this is not always required. Avoiding strenuous activity or certain medications (like nonsteroidal anti-inflammatory drugs) may be advised if your doctor recommends it.
What the Results Mean
Results are reported in milligrams per liter (mg/L) or micrograms per milliliter (µg/mL). While reference ranges vary by lab, very high levels (above 10 mg/L) often signal severe inflammation or infection, while moderate levels (3–10 mg/L) may indicate mild inflammation. Your doctor will interpret results in the context of your overall health and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CRP (High-Sensitivity)
Frequently asked questions
What does CRP measure?
Can CRP levels change with diet or exercise?
How often should I get a CRP test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy