Total Protein with Albumin Ratio (Serum)
This test measures the proportion of albumin relative to total protein in your blood serum, often used to assess protein balance and potential liver or kidney function issues.
["A useful tool to check protein distribution and possible health concerns in your blood."]
Key facts at a glance
- LOINC
- 42372-3
- Short code
- N men sg D Ag Islt Ql Aggl
- Synonyms
- N men sg D Ag Islt Ql Aggl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- aggl
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Albumin is a key protein in your blood that helps maintain fluid balance and supports immune function. Total protein includes albumin plus other proteins like globulins. An abnormal ratio may signal conditions like liver disease, kidney problems, or malnutrition.
How the Test Works
Blood is drawn from a vein, typically in your arm. The sample is sent to a lab where protein levels are measured using standard laboratory techniques, often including immunochemical methods to differentiate albumin from other proteins.
Common Conditions Affecting Results
Changes in this ratio can occur with liver disease (reduced albumin), kidney disease (altered protein breakdown), chronic inflammation, or conditions affecting protein synthesis.
What to Expect Before the Test
No special preparation is needed, but avoid heavy meals or alcohol before your blood draw. Wear loose clothing and inform your provider of any medications or conditions that may affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Albumin-to-Protein Ratio
Frequently asked questions
An abnormal albumin-to-protein ratio may indicate underlying health issues, such as liver dysfunction, protein-losing conditions, or malnutrition. Your healthcare provider will use these results alongside other tests and symptoms to guide diagnosis and treatment.
How long will it take to get my results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy