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Nucleic Acid Detection by Probe-Based Assay (e.g., for DNA)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of specific genetic material (DNA) using a molecular probe. It may be used to screen or confirm certain genetic conditions or infections.

Quick summary

["This test helps identify genetic material in a sample for diagnostic purposes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74536-4
Short code
N men sg W135 DNA Spec Ql NAA+probe
Synonyms
N men sg W135 DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test analyzes a sample for the presence of a specific DNA sequence using a molecular probe. This probe binds to the target DNA if it is present, allowing for detection. The method is highly sensitive and specific for identifying genetic material.

Why It Might Be Ordered

Your healthcare provider may order this test to screen for genetic conditions, infections (e.g., viruses), or other genetic abnormalities. It can also be used in research or specialized diagnostic settings.

Common Uses in Clinical Practice

Common applications include prenatal screening, infectious disease diagnosis (e.g., certain viruses), genetic counseling, and confirming hereditary conditions. It is not typically used for routine blood chemistry or metabolic testing.

Sample Collection and Preparation

A blood sample (whole blood) or other bodily fluid (e.g., saliva, urine) may be collected. The sample is processed to extract DNA, which is then analyzed by the probe-based assay. Results are qualitative (present or absent).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

What does a positive result mean?
A positive result means the test detected the specific genetic material (DNA) you were screened for. This may suggest a genetic condition, infection, or other underlying issue that needs further medical evaluation by your provider.
What if my test is negative?
A negative result means the targeted genetic material was not detected in the sample. However, this does not guarantee the absence of the condition or infection—other tests or follow-up may be needed. Always talk to your healthcare provider about next steps.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on the lab and complexity of the test. Your provider will contact you with the results once they are ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy