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Serum or plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein levels and kidney function.

Quick summary

["Total protein helps identify potential kidney issues or protein loss in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17330-2
Short code
N men sg Y Ag CSF Ql
Synonyms
N men sg Y Ag CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like kidney disease, liver problems, malnutrition, or certain types of infections. It can also help monitor protein loss in urine (proteinuria) or evaluate fluid balance in severe illnesses.

What to Expect Before the Test

No special preparation is needed unless instructed. You may have a small needle inserted into your arm for drawing blood. If you’re on a blood thinner, let your provider know before the test.

What the Results Mean

Higher-than-normal results may suggest liver disease, dehydration, or conditions causing excessive protein production. Lower-than-normal results could indicate malnutrition, liver disease, or kidney problems. Your provider will interpret results in relation to your health.

Common Conditions Monitored

This test is often used to monitor kidney function, detect protein loss in urine (e.g., in diabetic nephropathy), or assess protein deficiencies in chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What causes abnormal total protein levels?
Abnormal results can stem from medical conditions like liver disease, kidney problems, infections, or certain cancers. Lifestyle factors (e.g., diet, hydration) may also influence protein levels, but your provider will consider your full medical picture.
How often should I get this test?
Frequency depends on your health needs. Your provider may recommend regular testing if you have chronic conditions like kidney disease, liver issues, or if you’re at risk for malnutrition.
Can diet affect this test result?
Yes, diet (especially protein intake) and hydration can influence results. Avoiding high-protein foods for a few days before testing may help standardize results, but follow your provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy