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C-reactive protein (CRP) – Serum/Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by your liver in response to inflammation or infection in your body.

Quick summary

["CRP helps track inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42374-9
Short code
N men sg Y Ag Islt Ql Aggl
Synonyms
N men sg Y Ag Islt Ql Aggl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggl
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker that signals your body’s immune response. It rises when tissues are damaged, infections occur, or inflammatory conditions (like arthritis) are present. Your doctor may order this test to check for hidden inflammation or to guide treatment for conditions like heart disease or autoimmune disorders.

When This Test Is Done

CRP tests are commonly performed to evaluate general inflammation, monitor chronic conditions (e.g., rheumatoid arthritis), or assess risk for conditions like heart disease. They may also be used before or after surgeries to monitor healing or detect complications.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Avoid strenuous activity or taking anti-inflammatory medications (like ibuprofen) for 48 hours before testing, as they can affect results.

What the Results Mean

Results are interpreted based on your overall health and medical history. Higher-than-normal levels may indicate inflammation, infection, or other health issues. Your doctor will discuss findings in the context of your symptoms and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a key marker for diagnosing and managing inflammatory diseases. Low levels may suggest no active inflammation, while elevated levels can prompt further investigation into infections, autoimmune conditions, or other systemic issues. It’s also used to monitor treatment effectiveness in chronic inflammatory disorders.

Short name

CRP

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (like pneumonia or urinary tract infections), injuries, surgeries, or autoimmune diseases (like lupus or rheumatoid arthritis). Stress, certain medications, or even routine activities (like exercise) can temporarily affect CRP levels. Always discuss any changes with your healthcare provider.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready to review your results.
Can I take anything to lower my CRP levels?
While you can’t directly lower CRP levels, lifestyle changes like regular exercise, a balanced diet, and stress management may help reduce inflammation over time. Always follow your doctor’s advice regarding medications or supplements, as some may affect CRP levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy