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99mTc-DTPA Renal Clearance (Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products from your blood using a radioactive tracer. It helps assess kidney function and blood flow through the kidneys over time.

Quick summary

["Evaluates kidney function and blood flow with a specialized nuclear medicine test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43666-7
Short code
NM Kidney+ves Vs bld flow W Tc99mGHA IV
Synonyms
NM Kidney+ves Vs bld flow W Tc99mGHA IV
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test involves injecting a small amount of a radioactive substance (99mTc-DTPA) into your bloodstream. This tracer naturally passes through your kidneys and is excreted in urine. Special cameras detect how quickly the tracer leaves your blood, indicating how efficiently your kidneys filter waste.

Preparation for the Test

No special preparation is needed. You may have a small needle inserted to inject the tracer, followed by imaging scans. You’ll need to stay still during imaging to ensure accurate results.

How the Results Are Used

Results help doctors diagnose kidney conditions, such as blockages, infections, or reduced kidney function. It can also guide treatment decisions for conditions like kidney stones or vascular diseases.

Common Conditions Monitored

This test is often used to check kidney function in people with chronic kidney disease, urinary tract blockages, or those undergoing treatments that may affect kidney health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test provides critical insights into how well your kidneys are processing blood and filtering waste. Abnormal results may indicate issues like reduced kidney perfusion, structural problems, or systemic conditions affecting circulation. Early detection helps manage conditions before they worsen.

Short name

Renal Function Test

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if they suspect kidney disease, urinary blockages, or if you’re undergoing treatment that could impact kidney function, such as certain medications or radiation therapy.
What are the typical risks or side effects?
The injection may cause a brief sting or discomfort, and you might experience mild radiation exposure during imaging. Rarely, allergic reactions or temporary bruising can occur. No long-term risks are associated with this test.
How long does it take to get results?
Results are usually available within 24 to 48 hours, depending on your healthcare provider’s process. Your doctor will discuss them with you during a follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy