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Lipid profile with high-sensitivity measurements (HDL, LDL, triglycerides, total cholesterol, and possibly apolipoproteins)

Published: August 9, 2026Updated: August 16, 2026

This test measures key fats (lipids) in your blood, including cholesterol and triglycerides, which help assess your heart health risk.

Quick summary

["Check your cholesterol and fat levels to lower your risk of heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88944-4
Short code
NM Lung+Liver Views for AV shunt
Synonyms
NM Lung+Liver Views for AV shunt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Your blood sample is analyzed for several lipid components, including total cholesterol, high-density lipoprotein (HDL or 'good' cholesterol), low-density lipoprotein (LDL or 'bad' cholesterol), and triglycerides. Some labs may also check apolipoproteins or other related fats, depending on your order. These measurements help determine your overall lipid profile, which is critical for heart health.

Why It Matters for Your Health

High levels of certain fats, like LDL cholesterol or triglycerides, can increase your risk of developing conditions such as atherosclerosis (plaque buildup in arteries), heart attack, or stroke. This test helps healthcare providers identify these risks and guide treatment plans, such as diet, exercise, or medication.

How the Test Works

Your blood is drawn from a vein, typically in your arm. The sample is then processed and analyzed using advanced laboratory techniques, such as immunoassays or enzymatic methods, to measure lipid concentrations accurately. Some tests may use high-performance liquid chromatography (HPLC) for more detailed breakdowns.

Preparation and Sample Collection

For most lipid tests, you may need to fast for 9–12 hours before your blood draw to get accurate results. Avoid alcohol and heavy meals on the day of testing. Your healthcare provider will give you specific instructions based on your test order.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

What does a high or low result mean?
High LDL cholesterol or triglycerides may signal an increased risk of cardiovascular disease. Low HDL cholesterol may also raise this risk. Your results will be compared to general reference ranges provided by your lab, and your healthcare provider will interpret them in the context of your overall health.
How often should I get this test?
Healthcare providers often recommend lipid tests every 4–6 years for adults without known heart disease risk factors. If you have risk factors (like high blood pressure, diabetes, or a family history of heart disease), you may need testing more frequently, often every 1–2 years.
Can lifestyle changes affect my results?
Yes! Eating a heart-healthy diet, exercising regularly, and maintaining a healthy weight can improve your lipid levels. Smoking and excessive alcohol intake can also negatively impact your results, so quitting smoking and moderating alcohol use may help.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy