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Vitamin D Binding Protein (DBP) Total Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of vitamin D binding protein in your blood. It helps assess how well vitamin D is transported and utilized in your body.

Quick summary

["Vitamin D binding protein supports vitamin D metabolism and transport."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24888-0
Short code
NM Pulm system VP W 133Xe IH+Tc99mMAA IV
Synonyms
NM Pulm system VP W 133Xe IH+Tc99mMAA IV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of vitamin D deficiency, kidney or liver disease, or if you’re being evaluated for conditions like hypophosphatemia or certain metabolic disorders. It can also be part of broader screening for genetic or hormonal imbalances.

What Does the Result Mean?

Results may vary based on individual health, diet, and other factors. Abnormal levels could indicate conditions affecting protein synthesis, kidney function, or vitamin D metabolism, but interpretation depends on clinical context.

Sample Collection and Preparation

This test typically uses a blood sample drawn from a vein. The sample is processed into serum or plasma for analysis, often within 24 hours of collection to maintain accuracy.

Common Reasons for Testing

Tests like this are often included in evaluations for genetic disorders (e.g., pseudohypoparathyroidism), metabolic bone diseases, or when monitoring conditions like chronic kidney disease where protein metabolism is impacted.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated levels may suggest overproduction of DBP or conditions like nephrotic syndrome, while low levels could indicate liver disease, malnutrition, or genetic disorders impairing protein synthesis. However, DBP alone is rarely diagnostic; results are usually reviewed alongside clinical findings and other tests.

Short name

Total Vitamin D Binding Protein

Frequently asked questions

What causes abnormal vitamin D binding protein levels?
Abnormal levels may result from underlying conditions like liver or kidney disease, genetic disorders (e.g., hypophosphatasia), severe malnutrition, or certain medications that affect protein synthesis or metabolism. Always discuss symptoms and test results with your provider.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times and your healthcare provider’s workflow. Follow-up may be scheduled if additional testing or evaluation is needed.
Can diet affect vitamin D binding protein levels?
Dietary factors like vitamin D intake or protein-rich foods may indirectly influence overall protein levels, but vitamin D binding protein itself is primarily regulated by genetic and metabolic factors. Your provider will consider all relevant factors when interpreting results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy