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Serum or plasma **substance concentration** (unspecified analyte) measured by immunoassay (IA)

Published: August 9, 2026Updated: August 16, 2026

This test detects a specific substance in your blood using a sensitive immunoassay method. It helps identify certain conditions by measuring the presence or level of a particular protein, hormone, or other molecule.

Quick summary

["This test may help diagnose or monitor conditions related to your specific health concern."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
28528-8
Short code
NOGOODCHURCHEXPERIENCE
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
reported-living-hiv
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect an issue involving the substance being measured. Common reasons include evaluating symptoms like unusual fatigue, weight changes, or organ dysfunction, or to monitor a known condition that affects this substance’s levels.

What to Expect Before the Test

No special preparation is typically needed unless instructed by your provider. You may have a small needle inserted into your arm to draw blood. If you’re taking certain medications or have dietary restrictions, let your provider know beforehand.

What the Test Results Mean

Results are interpreted based on your clinical picture and may not have a single standard range. High or low levels could signal potential health issues, such as infections, autoimmune disorders, or metabolic imbalances. Your provider will discuss findings with you.

Common Conditions Monitored

This test may be used to diagnose or track conditions like infections, inflammatory diseases, hormonal imbalances, or certain cancers. For example, it could measure markers for thyroid disorders, kidney function, or immune system activity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Interpretation and Context

Frequently asked questions

How is this test performed?
The test involves drawing blood from a vein in your arm. The blood sample is then processed and analyzed using an immunoassay method, which detects and quantifies the specific substance in your serum or plasma. Results are compared to reference ranges relevant to your condition.
What are typical reference ranges for this test?
Reference ranges vary depending on the substance being tested and individual health factors. Your provider will use the results in conjunction with your symptoms, medical history, and other tests to determine if any action is needed.
Can lifestyle changes affect this test result?
Yes, certain lifestyle factors—such as diet, exercise, medications, or stress—may influence the levels of the substance being measured. Always inform your healthcare provider about any changes in your routine before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy