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Red Blood Cell Morphology Profile (Automated, Urine-Based Screening)

Published: August 9, 2026Updated: August 17, 2026

This test evaluates red blood cell (RBC) characteristics in urine, often used to screen for conditions affecting RBC shape or function.

Quick summary

["Urine-based RBC screening may help detect underlying blood disorders or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
99860-9
Short code
Non-dysmorphic RBC #/area UrnS AI Assis
Synonyms
Non-dysmorphic RBC #/area UrnS AI Assis
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
computer-assisted
CPT
85041
SNOMED
900000000000003001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

This test analyzes urine samples for abnormalities in red blood cell morphology, such as shape variations (e.g., spherocytes, elliptocytes) or presence of RBCs in urine (hematuria). While not a full blood smear, it may flag conditions that warrant further investigation, like kidney disease or inherited RBC disorders.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like blood in urine, unexplained fatigue, or if they suspect conditions like hematuria, kidney disease, or certain genetic blood disorders. It’s sometimes used as a preliminary screen before more detailed blood tests.

What to Expect Before the Test

No special preparation is needed. You’ll likely provide a urine sample (midstream or container) during a clinic visit. Avoid strenuous activity or certain medications (if instructed) that might affect urine color or composition.

What the Results Mean

Results may show normal RBC morphology in urine or indicate abnormal shapes/presence of RBCs. Abnormal findings often prompt follow-up tests, such as blood tests or urine culture, to diagnose underlying conditions.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

Why might this test be important?
Abnormal urine RBC morphology can signal conditions like kidney damage, urinary tract infections, or inherited blood disorders. Early detection may improve treatment planning and management of chronic conditions.
What does a positive result mean?
A positive result (abnormal RBCs in urine) may require further evaluation, such as blood tests or imaging, to determine the cause. Your provider will discuss next steps based on your symptoms and test results.
How often should I get this test?
Frequency depends on your health status. Routine screening is uncommon unless you have risk factors (e.g., kidney disease, family history of blood disorders). Follow your provider’s recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy