Skip to content

Cerebrospinal Fluid (CSF) Nonhematic Cell Count (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks the number of nonblood cells in your cerebrospinal fluid, which helps assess conditions affecting the brain and spinal cord.

Quick summary

["This simple test can help identify infections, inflammation, or other issues in your central nervous system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13525-1
Short code
Nonhematic Cells NFr CSF Manual
Synonyms
Nonhematic Cells NFr CSF Manual
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

The test focuses on counting cells in your CSF that are not red or white blood cells (hematic cells). These nonhematic cells may include lymphocytes, macrophages, or other immune cells. The result is qualitative, meaning it provides a general category (e.g., normal, increased, or decreased) rather than a precise number.

Why It’s Done

Doctors may order this test if you have symptoms like severe headaches, neck stiffness, fever, or neurological problems. It helps diagnose conditions such as meningitis, encephalitis, or other inflammatory or infectious processes in the central nervous system.

Sample Collection and Process

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The sample is then examined under a microscope to identify and count nonhematic cells. The test does not require fasting or special preparation.

What the Results Mean

Results are interpreted qualitatively rather than numerically. An elevated count of nonhematic cells might suggest an immune response, infection, or other inflammatory process. A normal result does not rule out all possible conditions, so further testing may still be needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CSF Cell Count (Qualitative)

Frequently asked questions

Why might my doctor want to know if my CSF has abnormal nonhematic cells?
Your doctor may use this test to investigate symptoms like persistent headaches, neurological deficits, or signs of inflammation in the brain or spinal cord. It can help determine whether an infection, autoimmune response, or other condition is affecting your central nervous system.
How long will I need to wait for my results?
Results are typically available within a few hours to a couple of days, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
No special preparation is needed for this test. You may eat and drink normally as usual, but avoid heavy physical activity before the lumbar puncture procedure.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy