Skip to content

Nonhematic Cells Count in Fluid

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of cells in a bodily fluid that are not red blood cells, often used to assess conditions affecting nonblood cells (e.g., inflammation, infection, or tissue damage).

Quick summary

["Understanding nonhematic cells can help diagnose conditions beyond red blood cells."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30457-6
Short code
Nonhematic Cells NFr Fld
Synonyms
Nonhematic Cells NFr Fld
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate conditions like infections (e.g., abscesses), inflammatory diseases, or certain types of cancer where nonblood cells (e.g., white blood cells, epithelial cells, or tumor cells) are present in unusual amounts in bodily fluids. It can also help monitor treatment responses or identify sources of abnormal fluid accumulation.

What Does the Result Mean?

Results may indicate an abnormal presence of nonhematic cells, suggesting conditions such as infections, tumors, or chronic diseases. However, interpretation depends on the fluid type (e.g., urine, cerebrospinal fluid) and clinical context. Your healthcare provider will discuss findings with you.

Common Conditions Influencing Results

Conditions like urinary tract infections (UTIs), kidney disease, or bladder cancer may show elevated nonhematic cells in urine. In cerebrospinal fluid, this could signal meningitis, brain tumors, or multiple sclerosis. Fluid from other sources (e.g., joint or pleural effusion) may reflect inflammation or infection.

Sample Collection and Preparation

The test typically requires a sample of bodily fluid (e.g., urine, spinal fluid, or joint fluid). Proper collection and handling are critical to avoid contamination or dilution. Your provider will guide you on preparation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Nonhematic Cells in Body Fluid

Frequently asked questions

What does a high or low count of nonhematic cells mean?
A high count may signal infection, inflammation, or malignancy, depending on the fluid type. A low count could indicate normalcy or underlying issues like severe dehydration (for urine) or immune suppression. Always correlate results with symptoms and other tests.
Can diet or medications affect this test?
Some medications (e.g., diuretics, chemotherapy) or dietary factors (e.g., excessive hydration) may influence fluid composition. Your provider will consider these factors during interpretation.
Is this test painful or invasive?
Pain or discomfort varies by sample type. For urine, it’s usually minimal. For spinal fluid, it involves a needle insertion (e.g., lumbar puncture), which may cause temporary soreness. Discuss risks with your provider.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy