Next-Generation Sequencing (NGS) Panel for Non-Invasive Prenatal Testing (NIPT) with Aneuploidy Detection and Deletion/Duplication Analysis
This test uses advanced genetic sequencing to check for certain chromosomal abnormalities and structural variations in your baby’s DNA, typically collected from a blood sample. It helps assess risks for conditions like Down syndrome or other genetic disorders.
["This test provides critical insights into your baby’s genetic health before birth, often used in prenatal care to guide decisions about next steps."]
Key facts at a glance
- LOINC
- 77018-0
- Short code
- Noninv fet 13+18+21 aneu pnl cfDNA seq
- Synonyms
- Noninv fet 13+18+21 aneu pnl cfDNA seq
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
Your blood sample is analyzed using high-tech sequencing technology to identify specific genetic markers. The test detects changes in chromosome counts (aneuploidy) and small deletions or duplications that may affect your baby’s health.
What to Expect Before the Test
No special preparation is needed. You’ll have a simple blood draw, similar to a regular blood test. Results are usually available within a few days to a week, depending on lab processing times.
Common Conditions This Test Can Detect
This test primarily screens for common chromosomal abnormalities (like Down syndrome, Edwards syndrome, or Patau syndrome) and certain genetic structural variations. It does not screen for all possible genetic conditions and may not detect every risk.
Limitations of This Test
While highly accurate for the conditions it tests, this test has some limitations. It may not detect all genetic disorders, and results can sometimes be inconclusive. It’s best used alongside other prenatal tests or ultrasounds for comprehensive care.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Results from this test can help identify high-risk pregnancies early, allowing healthcare providers to recommend additional testing (like amniocentesis or chorionic villus sampling) if needed. It can also provide reassurance if the results are normal, though further monitoring may still be advised.
Short name
NIPT with Genetic Variant Screening
Frequently asked questions
What does a positive result mean?
What if my results are normal?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy