: Nonliquefiable Semen Analysis with Total Volume and Volume Fraction Assessment
: This test evaluates a semen sample that does not liquefy normally, measuring total volume and the proportion of the sample that remains nonliquefied. It helps assess semen quality and identify potential causes of male fertility concerns.
[": A nonliquefying semen sample can affect fertility testing, so volume and fraction measurements help your care team interpret the results correctly."]
Key facts at a glance
- LOINC
- 80724-8
- Short code
- Non-liquefact vol/Total vol VFr Smn Est
- Synonyms
- Non-liquefact vol/Total vol VFr Smn Est
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- estimated
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What This Test Measures
: The test examines a semen specimen for its ability to liquefy after collection. It records the total sample volume and the fraction that stays nonliquefied, giving your provider information about the physical properties of the sample.
: Why Liquefaction Matters
: Normally, semen liquefies within a short time after collection, which allows sperm to move freely. When liquefaction is delayed or incomplete, it can interfere with accurate testing and may be associated with fertility issues.
: How the Sample Is Collected
: A semen sample is collected according to your clinic's instructions, usually after a period of abstinence. The laboratory observes the sample over time to judge liquefaction and measures the volumes involved.
: What Results Can Mean
: Results describe how much of the sample liquefied and how much did not. Your provider interprets these findings alongside sperm count, motility, and other semen analysis results to build a complete picture.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
: Nonliquefaction can be related to factors such as collection handling, infection, or other conditions affecting the prostate and seminal vesicles. Because interpretation depends on the full semen analysis and your medical history, discuss results with your provider rather than relying on this measurement alone.
Short name
: NONE
Frequently asked questions
: Does a nonliquefying sample mean I am infertile?
: Can the sample be retested?
: Should I change anything before collection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy