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: Nontreponemal or Treponemal Test Performed at 28 to 32 Weeks Gestation

Published: August 9, 2026Updated: August 16, 2026

: This test records whether a syphilis screening test (a nontreponemal or treponemal test) was performed during the 28-to-32-week window of pregnancy. It is used to confirm that recommended third-trimester syphilis screening was completed.

Quick summary

: This entry documents that a syphilis screening test was done at 28–32 weeks of pregnancy, supporting recommended prenatal screening.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75165-1
Short code
NONTREPONEMALORTREPONEMALTESTWASPERFORMEDAT2832WEEKSGESTATION
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cdc-cs
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Represents

: This is a documentation test that indicates whether a syphilis screening test was performed during a specific window of pregnancy (28 to 32 weeks gestation). Syphilis is a bacterial infection that can be passed from a pregnant person to the baby, so repeat screening in the third trimester is recommended for many pregnant patients.

: Nontreponemal vs Treponemal Tests

: Nontreponemal tests (such as RPR or VDRL) are general screening tests that can reflect active infection, while treponemal tests specifically detect antibodies to the bacterium that causes syphilis. Guidelines often use one type as a first screen and the other to confirm results, depending on the screening algorithm used.

: Why Timing in Pregnancy Matters

: Screening early in pregnancy and again at 28 to 32 weeks helps identify infections that may have been acquired after the first screen, allowing treatment before delivery. Treating syphilis during pregnancy greatly reduces the risk of passing the infection to the baby.

: How Results Are Interpreted

: Because this entry records whether a test was performed rather than a numeric value, results are typically reported as performed or not performed. Any positive screening result should be followed by confirmatory testing and discussed with a clinician, who will recommend next steps.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Documenting syphilis screening at 28 to 32 weeks gestation supports prenatal care quality and helps ensure timely treatment if infection is present. Because syphilis can be transmitted to the fetus and cause serious complications, repeat third-trimester screening is an important part of routine prenatal care, and positive results require prompt clinical follow-up.

Short name

: Syphilis Screening in Pregnancy (28–32 Weeks)

Frequently asked questions

: Does this test tell me whether I have syphilis?
: No. This entry documents whether a screening test was performed during 28 to 32 weeks of pregnancy. The actual screening test result and any follow-up testing determine whether infection is present.
: Why is syphilis screening repeated late in pregnancy?
: Repeat screening at 28 to 32 weeks can detect infections acquired after earlier testing, allowing treatment before delivery and reducing the chance of passing syphilis to the baby.
: What happens if my screening test is positive?
: A positive screening result is usually confirmed with a second type of test, and your clinician will discuss treatment and monitoring. Syphilis is treatable, and treatment during pregnancy helps protect both you and your baby.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy