Nordiazepam/Creatinine Ratio, Urine
Measures the benzodiazepine metabolite nordiazepam relative to urine creatinine, helping account for differences in urine concentration.
["This urine test can show whether nordiazepam, a metabolite of several benzodiazepines, is present in your body."]
Key facts at a glance
- LOINC
- 58367-4
- Short code
- Nordiazepam/Creat Ur
- Synonyms
- Nordiazepam/Creat Ur
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures nordiazepam in urine and compares it with the amount of creatinine in the same sample. Creatinine is used as a reference because urine concentration can vary widely.
Why might I need this test?
It may be used to check for recent exposure to certain benzodiazepine medicines. Your clinician may order it for medication monitoring, substance-use assessment, or when medication use needs to be confirmed.
How is the test performed?
A urine sample is tested in the laboratory for nordiazepam and creatinine. The laboratory may calculate the nordiazepam-to-creatinine ratio to help adjust for how concentrated the urine is.
How do I prepare for the test?
Collect the urine sample at the time and in the container specified by your healthcare provider or laboratory. Do not drink extra water solely to produce a sample, and tell the laboratory about any benzodiazepine medicines or other medications you have taken.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A detectable nordiazepam result can indicate recent exposure to a benzodiazepine that is metabolized to nordiazepam, although the result alone does not establish when or how the medicine was taken. An unexpectedly positive result may reflect prescribed medication, another medicine that produces nordiazepam, or possible interference from other substances. Your healthcare provider should interpret the result with your medication history and the reason for testing.
Short name
Urine Nordiazepam/Creatinine Ratio
Frequently asked questions
What is nordiazepam?
Why is the result divided by creatinine?
Does a positive result mean the medicine was taken recently?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy