Skip to content

Norepinephrine, mass concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of norepinephrine, a key chemical in your body’s fight-or-flight response, present in your blood plasma. It helps assess how well your nervous system is regulating stress hormones.

Quick summary

["Norepinephrine levels can signal nerve or adrenal issues, especially in chronic stress or certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47158-1
Short code
Norepineph 2h p 300 ug CLN PO Plas-sCnc
Synonyms
Norepineph 2h p 300 ug CLN PO Plas-sCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your doctor orders this test to check how well certain organs or systems in your body are working, to look for signs of illness, or to monitor a condition you already have. The results give important information that helps guide decisions about your diagnosis and treatment.

Your doctor may order this test to evaluate symptoms like high blood pressure, irregular heartbeat, or unexplained fatigue, which could indicate problems with your nervous system or hormone balance. It’s also used in diagnosing conditions like pheochromocytoma (a rare tumor affecting hormone production) or assessing nerve damage.

Your result shows how much of the measured substance was found in your sample. A value inside the normal range usually means typical body function, while a level that is too high or too low can point to a health problem that your healthcare provider may need to look into further.

Results are not provided with specific reference ranges here, but elevated levels may suggest overactivity of the adrenal glands or nerve system, while very low levels could indicate nerve dysfunction or medication side effects. Always discuss your results with your healthcare provider.

This test is commonly ordered during routine checkups, when you have unexplained symptoms, to screen for certain diseases, or to see how well a treatment is working over time. Your healthcare provider will decide how often you should have it based on your medical history and risk factors.

This test is often performed alongside other hormone or stress tests if you have symptoms like severe headaches, rapid heartbeat, or unexplained sweating. It may also be part of a broader evaluation for chronic stress, anxiety disorders, or certain neurological conditions.

Your sample, usually a small amount of blood drawn from a vein in your arm or a urine specimen, will be collected by a trained professional. Follow any instructions your care team gives you, such as fasting for a set number of hours or avoiding certain foods and medicines before the visit.

A blood sample is drawn from a vein in your arm, usually in the morning for consistency. The blood is processed to separate plasma, which is then sent to a lab for analysis. Avoid eating, drinking, or smoking for 12 hours before the test to ensure accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Norepinephrine Plasma

Frequently asked questions

Norepinephrine is a neurotransmitter and hormone produced by the adrenal glands and nerve cells. High levels can indicate conditions like pheochromocytoma, autonomic dysfunction, or severe stress responses. Low levels may signal nerve damage, certain medications, or adrenal insufficiency. Always correlate results with clinical symptoms and other tests for proper diagnosis.
How long does it usually take to get the results of this test back from the laboratory, and how will I receive them?
Results from this test are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results.
Can I take my regular medicines, vitamins, herbal products, or other supplements before this test, or should I skip any of them on the day of my appointment?
Yes, follow your doctor’s instructions carefully. Generally, avoid eating, drinking (except water), smoking, or consuming caffeine for at least 12 hours before your test to ensure accurate results.
The test involves a small needle inserted into your arm to draw blood, which may cause a brief sting or discomfort. Most people tolerate it well, and the area may feel sore for a few hours afterward. Your healthcare provider can provide details on how to minimize discomfort.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy