Fentanyl metabolite concentration (norFentanyl) in serum/plasma
This test measures the amount of norFentanyl, a metabolite of fentanyl, in your blood. NorFentanyl helps your body process and eliminate fentanyl, which is a powerful opioid pain medication.
["NorFentanyl levels help doctors monitor how your body handles fentanyl and assess pain control or potential overdose risk."]
Key facts at a glance
- LOINC
- 61086-5
- Short code
- Norfentanyl Gast Ql
- Synonyms
- Norfentanyl Gast Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’re taking fentanyl or other opioids, especially if you’re experiencing side effects like confusion, slow breathing, or unusual drowsiness. It can also be used to check how well your body is breaking down fentanyl in certain medical settings, such as pain management or addiction treatment.
What to Expect Before the Test
No special preparation is needed for this test. You’ll have a small needle inserted into your arm or vein to draw a blood sample. The process is quick and usually causes only minor discomfort. If you’re on blood thinners, let your provider know before the test.
What the Test Results Mean
Results are typically reported as a concentration (e.g., micrograms per liter). High levels may indicate recent fentanyl use, slower metabolism, or potential overdose risk. Low levels might suggest rapid clearance or reduced exposure. Your provider will interpret results in the context of your medical history and symptoms.
Possible Side Effects or Risks
Blood tests are generally safe, but rare risks include bruising, mild pain at the injection site, or a slight reaction to the needle. If you have a history of bleeding disorders or take anticoagulants, discuss this with your provider before the test.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
NorFentanyl
Frequently asked questions
How long does it take to get test results?
Can I drink water before this test?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy