Urinary Norfentanyl Mass Concentration (24-Hour Collection)
This test measures the amount of norfentanyl, a metabolite of fentanyl, in your urine over a 24-hour period. It helps assess recent exposure to fentanyl or fentanyl-related substances.
["This test helps track potential fentanyl exposure, often used in monitoring for pain management or substance use."]
Key facts at a glance
- LOINC
- 58383-1
- Short code
- Norfentanyl Ur Cfm-mCnc
- Synonyms
- Norfentanyl Ur Cfm-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- CPT
- 86430
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’ve been prescribed fentanyl or related medications, if you’re suspected of exposure to fentanyl (e.g., accidental ingestion, misuse), or if you’re undergoing treatment for opioid-related conditions. It can also be part of a broader evaluation for substance use or pain management monitoring.
What to Expect Before the Test
You’ll collect a 24-hour urine sample starting from the time you first notice the start of your urine stream (typically midnight to midnight). Follow your provider’s instructions carefully to ensure accurate results. Avoid certain medications or substances that might interfere with the test.
What Happens During the Test
The collected urine sample is sent to a lab for analysis using a specialized method to measure norfentanyl levels. No special preparation is needed beyond following the collection instructions.
What the Results Mean
Results are qualitative (positive or negative) and indicate whether norfentanyl was detected in your urine. A positive result suggests recent exposure to fentanyl or its metabolites, but it doesn’t confirm the source or intent behind exposure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results may prompt further evaluation, such as additional testing for fentanyl or other opioids, to understand the context of exposure. This can guide treatment decisions, especially if misuse or accidental exposure is suspected. Always discuss results with your healthcare provider to interpret them in the context of your medical history and symptoms.
Short name
Norfentanyl Urine Screen (24h)
Frequently asked questions
How long does it take to get results from this test?
Can I drink alcohol or take other medications before this test?
What does a positive result mean for my health?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy