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Norhydrocodone and Creatinine, Urine

Published: August 9, 2026Updated: August 16, 2026

This urine test measures norhydrocodone, a metabolite of hydrocodone, along with creatinine used to account for urine concentration.

Quick summary

["Detects recent hydrocodone exposure and helps interpret the result despite differences in urine concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61420-6
Short code
Norhydrocodone/Creat Ur
Synonyms
Norhydrocodone/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures norhydrocodone in urine. Norhydrocodone is a breakdown product of hydrocodone, and its measurement can help identify recent hydrocodone use.

Why might I need this test?

Urine testing may be used to monitor medication use, assess suspected drug exposure, or support requirements related to pain treatment or substance-use monitoring.

How is the test performed?

A urine sample is collected and analyzed in the laboratory. A screening method may be used first, with confirmatory laboratory testing when needed.

How do I prepare for the test?

Follow any instructions provided by the ordering clinician or laboratory. Be prepared to list current and recently used medicines, and do not intentionally drink large amounts of water before the sample is collected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine norhydrocodone

Frequently asked questions

Does a positive result mean someone took hydrocodone?
It indicates that exposure to hydrocodone or a related medication is likely, but timing and medication history should be reviewed. A clinician can help determine what the result means in context.
How long after taking hydrocodone can norhydrocodone be detected?
Detection generally lasts longer in urine than in blood, but the exact window varies with the dose, metabolism, hydration, and other factors.
Why is creatinine included?
Urine can range from very concentrated to very dilute. Creatinine helps the laboratory judge how much water is in the sample so the norhydrocodone result can be interpreted more reliably.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy