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Noroxycodone, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that detects noroxycodone, a metabolite of oxycodone, to help assess recent oxycodone exposure.

Quick summary

["A positive urine noroxycodone result generally indicates exposure to oxycodone or its metabolite."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61423-0
Short code
Noroxycodone/Creat Ur
Synonyms
Noroxycodone/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures noroxycodone in urine. Noroxycodone is a breakdown product, or metabolite, of oxycodone, a prescription opioid pain medicine.

Why might I need this test?

A clinician may order this test to assess oxycodone exposure, monitor use of prescribed opioid pain treatment, or evaluate a suspected drug-overdose situation. It may also be included as part of a broader urine drug screen.

How is the test performed?

You provide a urine sample in a collection cup. The laboratory analyzes it for noroxycodone, sometimes using an initial screening test followed by a more specific confirmatory method if needed.

How do I prepare for the test?

Follow the collection instructions provided by the clinic or laboratory. Drink fluids normally so you can provide urine, and tell the clinician about all medicines or supplements you take. Do not stop prescribed medication without medical advice.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine noroxycodone

Frequently asked questions

Does a positive result mean someone took oxycodone?
Usually, yes. A positive result indicates exposure to oxycodone or its metabolite, although it cannot determine exactly how much was taken or when.
Is noroxycodone the same as oxycodone?
No. Oxycodone is the original medicine, while noroxycodone is a metabolite formed when the body breaks it down.
Can this test show whether an opioid is being taken as prescribed?
Not by itself. The result must be interpreted with the treatment history, other urine tests, and clinical findings because it does not establish dose, timing, or misuse.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy