Fetal Autoantibody Profile (Autoimmune Markers in Fetal Circulation)
This test measures certain antibodies in your baby’s blood that may be linked to autoimmune conditions, helping assess potential risks during pregnancy.
["This screening helps identify if your unborn child may be exposed to autoimmune antibodies that could affect development."]
Key facts at a glance
- LOINC
- 62248-0
- Short code
- nRBC # Bld Fetus Auto
- Synonyms
- nRBC # Bld Fetus Auto
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- automated-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects a range of autoantibodies (such as antinuclear antibodies, rheumatoid factor, or others) present in fetal blood. These antibodies may originate from maternal circulation or be produced by the fetus itself, depending on genetic and immune factors.
Why It’s Done During Pregnancy
This screening is often performed when there’s a suspicion of autoimmune conditions in the mother or family history of autoimmune diseases, or if complications like recurrent miscarriages or unexplained fetal growth issues are present.
How the Test Works
A small sample of fetal blood (typically obtained via cord blood sampling or amniocentesis) is analyzed to identify specific autoantibodies using immunoassay methods. These tests detect the presence and levels of antibodies that could indicate an immune response.
What the Results Mean
Results may show elevated or detectable autoantibodies, which could signal an increased risk for autoimmune-related complications in fetal development. Further evaluation by your healthcare provider may include additional testing or monitoring.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Autoantibodies in Fetal Development
Short name
Autoantibody Screening in Fetus
Frequently asked questions
What might cause elevated autoantibodies in this test?
How often is this test repeated?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy