Bromocresol Blue Protein Electrophoresis (Serum)
This test measures protein distribution in your blood using a technique called electrophoresis, where proteins separate based on size and charge. Bromocresol Blue dye helps identify specific protein fractions.
["This test helps assess protein balance and potential abnormalities in blood protein composition."]
Key facts at a glance
- LOINC
- 772-4
- Short code
- nRBC # Bld Manual
- Synonyms
- nRBC # Bld Manual
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- manual-count
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins into distinct bands, each representing different protein types (e.g., albumin, globulins). Bromocresol Blue dye binds to proteins, allowing for visual differentiation of these fractions. The test evaluates the relative amounts of these proteins, which can indicate conditions like liver disease, kidney problems, or immune system disorders.
How the Test Works
A small blood sample is drawn and placed in a gel medium. An electric current is applied, causing proteins to migrate toward the opposite electrode. The dye highlights protein bands, which are then analyzed for concentration and distribution.
Common Uses
This test is often used to diagnose or monitor conditions affecting protein synthesis, such as liver disease (e.g., cirrhosis), kidney disease, or certain autoimmune disorders. It may also help evaluate protein-losing conditions or assess nutritional status.
When You Might Need This Test
Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or signs of liver/kidney dysfunction. It’s sometimes included in routine evaluations for patients with chronic illnesses or those undergoing certain treatments.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns can reveal underlying issues. For example, low albumin may indicate liver or kidney disease, while altered globulin levels could suggest immune dysfunction or inflammation. This test provides a snapshot of protein health that complements other lab findings.
Short name
Bromocresol Blue Protein Profile
Frequently asked questions
Why might my doctor recommend this test?
What does it mean if my results are abnormal?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy