C-reactive protein (CRP) with high-sensitivity measurement
This test measures a protein produced by the liver in response to inflammation, helping doctors assess low-level inflammation in your body.
["hs-CRP helps track subtle inflammation that may not show up in other tests."]
Key facts at a glance
- LOINC
- 70171-4
- Short code
- nRBC NFr Prt
- Synonyms
- nRBC NFr Prt
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why hs-CRP Matters in Your Health
hs-CRP (high-sensitivity C-reactive protein) is a blood test that detects very small amounts of inflammation in your body. While inflammation is a normal part of healing, chronic or low-grade inflammation can be linked to conditions like heart disease, diabetes, and autoimmune disorders. This test is often used alongside other health checks to monitor risk or guide treatment decisions.
How the Test Works
Your blood sample is analyzed using a sensitive immunoassay method to detect CRP levels. The test measures the protein’s concentration in the blood, which can reflect ongoing inflammation even when symptoms aren’t present.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into your arm for a blood draw, similar to other routine blood tests. If you’re taking blood thinners, let your healthcare provider know before the test.
Common Uses and Why It’s Ordered
Doctors may order hs-CRP to evaluate risk for cardiovascular diseases, monitor chronic conditions like arthritis or lupus, or check for signs of infection or inflammation after surgery or injury. It’s also used in research and screening programs to assess general health trends.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
hs-CRP
Frequently asked questions
What does a high hs-CRP level mean?
What does a low hs-CRP level mean?
Can hs-CRP levels change with lifestyle?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy