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Serum or plasma concentration of uric acid (substance concentration measurement)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of uric acid in your blood, a natural substance produced when your body breaks down certain foods and substances, including purines found in meat and seafood.

Quick summary

["Uric acid helps protect joints and other tissues, but high levels can lead to health issues like gout or kidney stones."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
62442-9
Short code
nRBC Snv Auto-Rto
Synonyms
nRBC Snv Auto-Rto
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test to check for conditions like gout, kidney disease, or to monitor treatment for conditions that affect uric acid levels, such as certain cancers or medications that influence purine metabolism.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves a blood draw. Avoid alcohol and certain medications (like aspirin) for 24 hours beforehand if instructed.

How the Test Is Performed

A blood sample is taken from a vein, usually in your arm, and sent to a lab for analysis. The lab measures uric acid levels using a specialized method, often an automated assay that detects the chemical’s presence.

Possible Results and Interpretation

Results are compared to standard reference ranges, though individual ranges can vary by lab. High uric acid levels may signal conditions like hyperuricemia, while very low levels might warrant further investigation for metabolic or genetic causes.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: fluid

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated uric acid is most commonly linked to gout, kidney problems, or genetic disorders. It can also indicate overproduction of purines or impaired kidney function, which may require lifestyle adjustments, medication, or medical management to prevent complications like joint damage or kidney stones.

Short name

Uric Acid

Frequently asked questions

What causes uric acid levels to be high?
High uric acid levels can result from diet (rich in purines), certain medical conditions (like kidney disease or diabetes), or medications. Genetics may also play a role in some cases.
What happens if my uric acid levels are too low?
Low uric acid levels are less common but may signal conditions like Fanconi syndrome (a kidney disorder) or certain genetic disorders. Your doctor may recommend further testing to identify the cause.
Do I need to avoid certain foods before this test?
While no strict diet restrictions apply, avoid high-purine foods (like organ meats, shellfish, or alcohol) for a few days before testing if your doctor advises it, as they can temporarily raise uric acid levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy