C-reactive protein (CRP) with high-sensitivity measurement
This test measures a protein in your blood that rises when your body is fighting inflammation or infection.
["hs-CRP helps track inflammation, which may signal underlying health concerns like heart disease or autoimmune conditions."]
Key facts at a glance
- LOINC
- 85098-2
- Short code
- NTBC DBS LC/MS/MS-sCnc
- Synonyms
- NTBC DBS LC/MS/MS-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- lc-ms-ms
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why hs-CRP Matters
High-sensitivity CRP (hs-CRP) is a marker for low-grade inflammation in your body. It’s often used alongside other tests to assess risk for conditions like cardiovascular disease or to monitor treatment responses in chronic illnesses.
What to Expect During Testing
A blood sample is drawn from a vein, usually in your arm. The test is quick and typically done in a lab. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. No special preparation is needed unless instructed otherwise.
Common Uses
Doctors may order hs-CRP to evaluate risk for heart disease, monitor conditions like rheumatoid arthritis or lupus, or check for signs of infection or inflammation after surgery or illness.
When Results Might Be High or Low
Elevated hs-CRP levels may indicate inflammation, infections, or conditions like heart disease. Lower levels might suggest reduced inflammation, but they don’t always mean you’re healthy. Results depend on many factors, including age, health status, and medications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
hs-CRP
Frequently asked questions
What does a high hs-CRP level mean?
Can I lower my hs-CRP level?
Does hs-CRP change with age?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy