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Natriuretic Peptide, Serum (B-type, measured by immunoassay)

Published: August 9, 2026Updated: August 17, 2026

This test measures a protein produced by your heart in response to pressure or volume overload, helping assess heart strain or fluid overload.

Quick summary

["Helps doctors check if your heart is working too hard due to conditions like heart failure or fluid retention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
83108-1
Short code
NT-proBNP SerPl IA-sCnc
Synonyms
NT-proBNP SerPl IA-sCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
83880
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your doctor may order this test if you have symptoms like shortness of breath, swelling, or fatigue, or if you have a history of heart problems. It can also help monitor conditions like heart failure or guide treatment decisions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’re on a fluid-restricted diet, follow your doctor’s instructions.

What the Results Mean

Higher-than-normal levels may indicate your heart is working harder than usual, possibly due to fluid buildup or heart failure. Lower-than-normal levels might suggest less stress on your heart. Your doctor will interpret results in the context of your overall health.

Common Conditions Monitored

This test is often used to diagnose or monitor heart failure, pulmonary edema, or conditions causing fluid retention in the body.

Reference range

Normal: <100 pg/mLN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Elevated BNP levels often signal heart strain, helping differentiate between heart failure and other causes of symptoms like shortness of breath. It’s particularly useful in emergency settings or for guiding treatment adjustments in chronic heart conditions.

Short name

BNP (Serum)

Frequently asked questions

What triggers this test?
Your doctor may order it if you have symptoms like chest discomfort, rapid heartbeat, or swelling, especially if you have a history of heart disease. It’s also used to evaluate heart function in patients with fluid overload or suspected heart failure.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing time. Your doctor will discuss the findings with you.
Can I eat or drink before this test?
No special diet is required, but if your doctor has instructed a fluid restriction, follow their guidance. Standard blood tests can be done after fasting if needed for other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy