Neurotrophic Receptor Gene Rearrangement Panel (TRKA/B/C)
This test checks for genetic rearrangements in the neurotrophic receptor genes TRKA, TRKB, and TRKC, which are involved in nerve cell development and function. These genes can be rearranged due to certain genetic conditions or cancers.
This test helps diagnose conditions linked to abnormal TRK receptor function, such as certain types of neuroblastoma or other genetic disorders affecting nerve development.
Key facts at a glance
- LOINC
- 93813-4
- Short code
- NTRK1+NTRK2+NTRK3 rearr Tiss
- Synonyms
- NTRK1+NTRK2+NTRK3 rearr Tiss
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained nerve pain, developmental delays, or a family history of genetic disorders involving nerve cells. It’s also sometimes used in cancer diagnostics, particularly for neuroblastoma or other solid tumors.
What to Expect During the Test
A blood sample is typically taken from a vein in your arm. The sample is then analyzed in a lab to detect genetic rearrangements in the TRK receptor genes. Results may take several days to weeks, depending on the lab’s process.
Possible Results and Next Steps
If rearrangements are found, this may indicate a genetic condition or cancer requiring further evaluation, such as additional genetic testing or treatment planning. If no rearrangements are detected, it may not rule out other causes of symptoms.
What This Test Means for Your Health
Finding rearrangements in TRK genes can help guide treatment options, especially in pediatric cases like neuroblastoma. For adults, it may support diagnosis of rare nerve-related cancers or syndromes. Always discuss results with your doctor for personalized guidance.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Genetic Rearrangements in TRK Genes
Short name
TRK Receptor Gene Testing
Frequently asked questions
What causes this test to be performed?
How long will I need to wait for results?
Can this test be done on other body fluids besides blood?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy