Neurotrophic Receptor Gene Mutation Detection (Blood)
This test checks for specific genetic changes in a protein-related gene that may be linked to certain cancers or other conditions affecting nerve cells.
["Helps assess potential genetic risks or treatment responses related to rare genetic mutations."]
Key facts at a glance
- LOINC
- 106873-3
- Short code
- NTRK gene Mut Anl Bld/T
- Synonyms
- NTRK gene Mut Anl Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have a family history of certain cancers (such as neuroblastoma, colorectal cancer, or thyroid cancer), or if you have symptoms like unexplained pain, swelling, or nerve-related issues. It may also be used to guide treatment decisions for patients with known cancer or suspected genetic predisposition.
This test analyzes a small sample of your blood to detect mutations in the NTRK gene, which encodes proteins involved in cell signaling. Advanced laboratory techniques identify these genetic changes by comparing your DNA to a reference database.
The test is typically done through a simple blood draw, and results are usually available within 1–2 weeks, depending on the laboratory.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn in the morning. Wear a loose shirt and avoid heavy exercise the day before.
A healthcare professional will insert a small needle into your arm to collect a blood sample. You may feel a slight pinch, but it usually doesn’t cause discomfort. The process takes only a few minutes.
After the test, you can resume normal activities immediately. Apply gentle pressure to the site to stop any bleeding, and check for signs of infection (like redness or swelling) over the next few days.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Mutations in the NTRK gene are rare but can be associated with certain cancers, such as neuroblastoma, thyroid cancer, or colorectal cancer. These mutations may also play a role in other rare genetic conditions affecting nerve function. If detected, your provider may discuss treatment options, including targeted therapies that can specifically address the genetic change.
Short name
NTRK Gene Mutation Test
Frequently asked questions
How long will I need to wait for my results?
What does a positive or negative result mean?
Can this test be used to monitor my condition over time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy