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Neurotrophic Receptor Gene Mutation Test (Blood)

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic mutations in the NTRK genes found in blood cells. These mutations may be linked to certain cancers or other genetic conditions.

Quick summary

["This test helps doctors understand if you may have a genetic change that could affect your health, especially in cancer treatment planning."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106874-1
Short code
NTRK gene Mut Tested Bld/T
Synonyms
NTRK gene Mut Tested Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a suspected or diagnosed cancer (such as certain types of solid tumors or leukemias), a family history of certain cancers, or if you’re considering targeted cancer treatments that rely on knowing your genetic makeup.

What to Expect Before the Test

You’ll typically have a small blood sample drawn from a vein in your arm, similar to other blood tests. No special preparation is usually needed, but always follow your provider’s instructions.

What the Test Measures

The test looks for mutations in the NTRK genes, which are involved in signaling pathways that control cell growth and survival. These mutations can be present in cancer cells or sometimes in other tissues.

How the Results Are Used

Results can help determine if a targeted therapy (a drug designed to work with specific genetic changes) might be effective for your condition. It may also guide decisions about treatment options or monitoring.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

NTRK Gene Mutation Test

Frequently asked questions

How long will it take to get my results?
Results from this test can take several weeks to a few months, depending on the laboratory and whether additional testing is needed for confirmation.
What does a positive result mean?
A positive result means the test detected a mutation in the NTRK genes. This may indicate a higher likelihood of certain cancers or guide treatment decisions, such as using targeted therapies that target these mutations.
Can this test be done on other types of specimens?
This test is primarily performed on blood samples, as it requires DNA from cells. However, in some cases, other tissues (like tumor samples) may be used, depending on the clinical situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy