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Substance Content of Maternal Blood for Pregnancy-Related Biomarkers (Serum/Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures certain substances in your blood to help monitor your health and the well-being of your developing baby during pregnancy. It may be used to identify potential challenges early.

Quick summary

Early detection of pregnancy-related health concerns through blood tests.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
93084-2
Short code
NULLIPAROUSPREGNANCYOUTCOMESSTUDYMONITORINGMOTHERSTOBEDIFFICULTIESINPREG
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
numom-b
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you are at higher risk for pregnancy complications, such as gestational diabetes, preeclampsia, or other maternal or fetal issues. It can also help track how your body is adjusting to pregnancy, especially if you have had difficulties in past pregnancies.

What to Expect Before the Test

You will likely have a simple blood draw, usually taken from a vein in your arm. No special preparation is needed, but inform your provider about any medications or supplements you’re taking.

What the Test Measures

This test detects levels of various substances in your blood, such as proteins, hormones, or other biomarkers that can signal how your body is functioning during pregnancy. These may include markers for inflammation, metabolic health, or organ function.

Common Uses and Benefits

The results help your healthcare team assess risks early, plan interventions if needed, and ensure both you and your baby stay healthy. It may also help identify if you need additional support or monitoring.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in personalized prenatal care by providing data to guide decisions about care, such as lifestyle adjustments, medication adjustments, or referrals to specialists. Early identification of potential issues can improve outcomes for both mother and baby.

Short name

Pregnancy Biomarker Screening

Frequently asked questions

Will I need to fast before this test?
No fasting is required for this blood test. However, always follow your healthcare provider’s instructions for any specific preparations.
What does a low or high result mean?
Results can vary based on your health and pregnancy stage. Your provider will interpret the results in the context of your overall health and discuss any findings with you.
How often will I need this test?
The frequency depends on your pregnancy history, health status, and provider recommendations. Some women may need it once, while others may have it multiple times during pregnancy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy