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Serum or Plasma Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10233-5
Short code
O2 Ct LA-sCnc
Synonyms
O2 Ct LA-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate kidney health, monitor chronic kidney disease, detect early kidney problems, or assess fluid balance in conditions like heart failure.

What Does a High or Low Result Mean?

High levels may indicate kidney issues, dehydration, or muscle disorders. Low levels could suggest overhydration, liver disease, or certain medications affecting kidney function.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure creatinine concentration using a standard method.

What Should You Do Before the Test?

Avoid strenuous exercise or heavy meals 24 hours before the test. Stay hydrated unless instructed otherwise by your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

Will I feel any pain or discomfort during the blood draw?
You may feel a slight pinch or sting when the needle is inserted, but it usually goes away quickly. Most people experience minimal discomfort afterward.
Can I eat or drink normally before this test?
You can eat and drink normally unless your doctor specifies otherwise, as creatinine levels are not affected by food or drink.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy