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Serum or plasma concentration of total protein

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall protein levels and kidney function. Protein is essential for many bodily functions, including maintaining healthy tissues and supporting immune responses.

Quick summary

["Your blood protein levels can indicate kidney health or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10247-5
Short code
O2 Ct PW-sCnc
Synonyms
O2 Ct PW-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order a total protein test to check for conditions like kidney disease, liver problems, malnutrition, or certain types of infections. It can also help diagnose or monitor conditions such as multiple myeloma, inflammatory diseases, or fluid imbalances in the body.

What Does the Test Involve?

A blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab where it is analyzed to determine the total protein concentration. No special preparation is typically required, but you may be asked to avoid certain medications or foods for a short time before the test.

What Are Common Results and Their Meanings?

While specific reference ranges vary by lab, lower than expected protein levels might suggest malnutrition, kidney disease, or liver problems. Higher than expected levels could indicate conditions like multiple myeloma, severe dehydration, or certain inflammatory diseases. Your healthcare provider will interpret the results in the context of your overall health and medical history.

What Does This Test Tell Me About My Health?

Total protein levels can give clues about how well your kidneys are filtering waste and how your liver is producing proteins. Abnormal results may prompt further testing to identify underlying causes, such as specific blood tests or imaging studies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What does a total protein test measure?
This test measures the combined amount of all proteins in your blood, including albumin and globulins. It does not differentiate between specific types of proteins.
How long does it take to get the results of this test?
Results are typically available within a few days, depending on your lab’s processing time. Your healthcare provider will contact you once the results are ready.
Can I eat or drink anything before this test?
No special diet is required, but you may be advised to avoid certain medications or supplements for a short time before the test, depending on your specific situation. Always follow your healthcare provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy