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Oxidative stress marker (serum/plasma concentration) – Total Antioxidant Capacity

Published: August 9, 2026Updated: August 16, 2026

This test measures the overall ability of your blood to neutralize harmful free radicals, which can cause cell damage. It helps assess your body’s oxidative balance and may be used to monitor conditions linked to oxidative stress.

Quick summary

["Your blood’s ability to protect itself from oxidative damage is evaluated here."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10236-8
Short code
O2 Ct RA.low-sCnc
Synonyms
O2 Ct RA.low-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Total antioxidant capacity reflects the combined activity of various antioxidants in your blood, such as vitamins (like vitamin C and E), enzymes, and other molecules that neutralize free radicals. Free radicals are unstable molecules that can damage cells and contribute to aging and disease. This test provides a snapshot of your body’s natural defense against oxidative stress.

Why Might You Need This Test?

Doctors may order this test if you have or are at risk for conditions linked to oxidative stress, such as chronic inflammation, cardiovascular disease, certain cancers, or metabolic disorders. It can also be used to monitor treatment responses or assess overall health in patients with long-term conditions.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is then analyzed in a lab to measure the total antioxidant capacity. The results are typically reported as a concentration value, though exact reference ranges can vary by lab.

What Are Common Uses?

This test is often used as part of broader health assessments, especially in research or specialized clinical settings. It may help identify individuals with elevated oxidative stress, track changes over time, or guide management of certain health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Antioxidant Status (TAS)

Frequently asked questions

What does a high or low result mean?
A high total antioxidant capacity may indicate strong natural defenses against oxidative damage, but it can also sometimes reflect chronic inflammation or other metabolic processes. A low result could suggest increased oxidative stress, which may be linked to health risks like heart disease or premature aging.
How often should I get this test?
There is no standard schedule for this test as it is less commonly ordered than routine blood panels. Your healthcare provider will determine if and when it’s needed based on your health status and symptoms.
Can lifestyle changes affect this test?
Yes, diet, exercise, and certain supplements (like antioxidants) can influence your total antioxidant capacity. Eating a balanced diet rich in fruits, vegetables, and healthy fats may support higher antioxidant levels, while smoking or excessive alcohol intake may reduce them.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy