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Serum or Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood, often used to identify abnormalities like infections, liver disease, or certain cancers.

Quick summary

["Helps detect unusual protein patterns that may signal underlying health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57708-0
Short code
OA defects NBS comment
Synonyms
OA defects NBS comment
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Protein electrophoresis separates blood proteins into fractions (e.g., albumin, globulins) based on size and charge. This helps identify shifts in protein composition that could indicate conditions like multiple myeloma, chronic inflammation, or liver/kidney disorders.

Common Uses

Doctors may order this test to diagnose or monitor conditions like autoimmune diseases, infections, or inherited protein disorders. It’s also used in screening for conditions affecting protein production or breakdown.

Sample Collection

A small blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma for testing. No special preparation is needed, but fasting may be advised depending on clinical context.

Preparation & Timeline

No special preparation is required, but inform your provider about medications or recent illnesses. Results may take 1–3 business days, depending on lab workflow.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal electrophoresis patterns can reveal hidden protein disorders, infections, or metabolic conditions. For example, elevated gamma globulins may suggest multiple myeloma, while low albumin could signal liver disease or malnutrition. Always correlate results with clinical symptoms.

Short name

Protein Electrophoresis (Qual)

Frequently asked questions

Why might I need this test?
Your doctor may recommend it if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect a condition affecting protein levels in your blood.
How long will I wait for results?
Results are typically ready within 1–3 days, but timing can vary. Your provider will discuss findings with you during your follow-up visit.
What if my results are abnormal?
Abnormal results may prompt further testing (e.g., confirmatory assays, imaging) or additional bloodwork. Your doctor will explain next steps based on your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy