Ovarian Cancer Risk Assessment Profile (Prognostic Note)
This test evaluates biomarkers and genetic factors that may help assess your risk for ovarian cancer, often used in conjunction with other clinical information.
["This profile supports personalized risk evaluation for ovarian cancer, not a definitive diagnosis."]
Key facts at a glance
- LOINC
- 100493-6
- Short code
- OBGYN OP Prog note
- Synonyms
- OBGYN OP Prog note
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- obstetrics-and-gynecology
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test includes genetic markers and protein-based assessments that may indicate increased susceptibility to ovarian cancer. These may include: - Genetic variants (e.g., BRCA1/2, PALB2) associated with hereditary cancer risk. - Tumor markers (e.g., CA-125, HE4) that can reflect ovarian cancer presence or progression. - Other biomarkers (e.g., specific protein levels) that may correlate with ovarian cancer risk or behavior.
How the Results Are Used
Results help healthcare providers tailor risk management strategies, such as: - Recommendations for surveillance (e.g., regular imaging or CA-125 monitoring). - Guidance on genetic counseling and family screening if applicable. - Adjustments to preventive measures (e.g., prophylactic surgeries or medications).
Important Notes About the Test
This is a **prognostic note**—not a diagnostic test. It provides additional context alongside clinical findings, not a standalone evaluation. Results should be interpreted by your healthcare team in the context of your medical history and symptoms.
Who Might Need This Test
This profile is typically ordered for individuals with: - A personal or family history of ovarian cancer or related cancers (e.g., breast, colon). - Symptoms suggestive of ovarian cancer (e.g., persistent bloating, pelvic pain). - As part of a broader risk assessment in high-risk settings (e.g., genetic counseling clinics).
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
This test does not replace a definitive diagnosis but may identify individuals at higher risk who could benefit from closer monitoring or preventive interventions. Early detection and risk stratification are critical for managing ovarian cancer.
A positive result may indicate an increased likelihood of ovarian cancer or genetic predisposition. Your healthcare provider will discuss next steps, which may include further genetic testing, imaging, or surveillance plans tailored to your situation.
No, this test is not diagnostic. It provides risk information and should be used alongside clinical evaluation, imaging, and other tests (e.g., ultrasound, CA-125 levels) for accurate diagnosis.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy