Skip to content

Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Albumin-to-Creatinine Ratio (UACR) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures your long-term blood sugar control (HbA1c) and evaluates kidney function by comparing albumin (a protein) to creatinine (a waste product) in your urine, using a 24-hour urine sample. It helps assess both diabetes management and kidney health together.

Quick summary

["This test combines blood sugar control and kidney health in one evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24364-2
Short code
Obstetric 1996 Pnl Ser+Bld
Synonyms
Obstetric 1996 Pnl Ser+Bld
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have diabetes, high blood pressure, or a family history of kidney disease. It helps monitor how well your blood sugar is controlled over time and checks for early kidney damage that diabetes can cause.

What to Expect Before the Test

For the UACR part, you’ll need to collect all urine for 24 hours in a special container. For the HbA1c, a simple blood draw from your arm is needed. Follow any specific instructions your lab provides, such as avoiding certain foods or drinks before urine collection.

What the Test Results Mean

HbA1c results show average blood sugar levels over the past 2–3 months. Higher values indicate poorer blood sugar control. The UACR ratio compares albumin (a sign of kidney damage) to creatinine (a measure of kidney function). Elevated albumin levels may signal kidney problems.

Common Causes of Abnormal Results

High HbA1c levels often mean uncontrolled diabetes, while high UACR may indicate kidney damage from diabetes, high blood pressure, or other conditions. Low UACR could suggest normal kidney function or low protein intake.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for people with diabetes to prevent long-term complications like kidney disease, heart disease, or nerve damage. Early detection of kidney issues helps adjust treatments like blood pressure or diabetes medications to protect your health.

Short name

HbA1c + UACR Profile

Frequently asked questions

What does an abnormal HbA1c result mean?
An abnormal HbA1c result means your blood sugar levels have been consistently higher than recommended over time. This could indicate poor diabetes management or the need for adjustments in your treatment plan, such as medication or lifestyle changes.
How does the UACR test help with kidney health?
The UACR test helps detect early kidney damage by measuring protein loss in urine relative to kidney function. High values may signal kidney issues, even if kidney function tests (like creatinine clearance) appear normal.
Can diet affect my UACR results?
Yes, diet can influence UACR results. High-protein diets or certain foods may temporarily affect albumin levels in urine. Your healthcare provider may recommend specific dietary guidelines or timing of tests to get accurate results.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy