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Urine Albumin-to-Creatinine Ratio (ACR) or Urinary Albumin-to-Creatinine Ratio

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of albumin (a protein) to creatinine (a waste product) in your urine. It helps assess how much protein is being lost in your kidneys over time.

Quick summary

["A useful tool for early kidney disease detection by tracking protein loss in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35096-7
Short code
OB US Pnl
Synonyms
OB US Pnl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Kidney Health

Kidneys normally filter waste and excess substances from your blood, including small amounts of protein like albumin. If your kidneys are damaged, they may allow more protein to leak into your urine. This test helps detect early signs of kidney problems by measuring the ratio of albumin to creatinine, which is a stable measure of urine volume.

How the Test Works

A small urine sample is collected, typically over a 24-hour period or a single random sample. The lab analyzes the sample to determine the concentration of albumin and creatinine. The ratio helps identify if protein is being lost in urine, which can indicate kidney issues.

When You Might Need This Test

Your doctor may recommend this test if you have symptoms like swelling, frequent urination, fatigue, or high blood pressure. It’s also used in screening for diabetes, hypertension, or kidney disease, especially in people with risk factors like family history or obesity.

What to Expect Before the Test

You’ll need to collect a urine sample, often over 24 hours (unless specified otherwise). Follow your doctor’s instructions carefully to ensure accurate results. Avoid certain foods or medications that might affect protein levels, if instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Albumin/Creatinine Ratio

Frequently asked questions

How does this test help doctors monitor kidney health?
This test provides a quick and non-invasive way to detect early kidney damage by measuring protein loss in urine. High albumin levels in urine (microalbuminuria) can signal kidney problems, especially in people with diabetes or high blood pressure, allowing for timely treatment to slow progression.
What does a high or low result mean?
A high albumin-to-creatinine ratio suggests increased protein loss, which may indicate kidney damage. A normal ratio means your kidneys are filtering waste properly. Your doctor will interpret results in the context of your overall health and symptoms.
Can diet or medications affect this test?
Yes, certain foods (like high-sodium or high-protein diets) or medications (e.g., NSAIDs like ibuprofen) may temporarily affect protein levels. Follow your doctor’s guidance on diet or supplements to avoid interference.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy