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Serum Immunoglobulin and Allergen-Specific IgE Profile (Screening Mix)

Published: August 9, 2026Updated: August 17, 2026

This blood test measures levels of Immunoglobulin E (IgE) and checks for specific antibodies to common allergens, helping identify potential allergic reactions.

Quick summary

["IgE and allergen-specific tests help pinpoint possible allergies and guide allergy management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82091-0
Short code
Occup Allerg Mix4 IgE RAST
Synonyms
Occup Allerg Mix4 IgE RAST
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test includes a general IgE measurement and checks for IgE antibodies to multiple common allergens, such as pollen, dust mites, pet dander, mold, and certain foods. These antibodies are part of the body’s immune response to allergens.

Why Might You Need This Test?

Your doctor may recommend this test if you have symptoms like sneezing, itching, rash, or difficulty breathing that suggest allergies. It can also help confirm a diagnosis before allergy treatments like immunotherapy.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab for analysis using immunoassay methods to detect IgE and allergen-specific IgE levels.

What Are the Results Typically Used For?

Results help identify which allergens may trigger your symptoms, allowing your doctor to create a personalized treatment plan, such as avoiding allergens or prescribing allergy medications.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used for diagnosing allergic conditions and guiding treatment decisions. Elevated IgE levels or specific IgE antibodies to allergens can confirm allergies and direct further management, such as allergy testing or immunotherapy.

Short name

IgE & Allergy Panel

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on lab processing times.
What does a high IgE level mean?
A high IgE level may indicate an allergic reaction or heightened sensitivity to certain substances. However, it doesn’t always mean you’ll have symptoms unless specific allergens are present in your environment or diet.
Can I take anything before the test?
No special preparations are needed for this test. However, inform your doctor about any medications you’re taking, as some may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy