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Serum Immunoglobulin (Ig) Profile with Allergen-Specific Testing (Screening Mix)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of different types of antibodies (immunoglobulins) in your blood, including specific responses to common allergens. It helps identify whether you have an allergic reaction risk or existing sensitivities.

Quick summary

["This screening helps guide allergy management and treatment options by detecting potential immune responses to allergens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15239-7
Short code
Occup Allerg Mix5 IgE Ql
Synonyms
Occup Allerg Mix5 IgE Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Your blood contains several types of immunoglobulins (IgA, IgE, IgG, IgM), each playing a role in immune defense. This test includes a mix of allergen-specific antibodies (IgE) and general immunoglobulin levels to assess your immune response profile. Some components may also detect IgG antibodies to specific allergens, which can indicate past exposure or immune memory.

Why Might You Need This Test?

A doctor may recommend this screening if you have symptoms like sneezing, itching, hives, or breathing difficulties that suggest allergies. It can also help evaluate conditions like asthma, eczema, or chronic sinusitis that may be linked to allergic reactions. Some patients are tested as part of a broader allergy workup before receiving allergy immunotherapy (allergy shots).

How Is the Test Performed?

A small blood sample is drawn from your arm, typically in a clinic or lab. The blood is processed to separate serum (the liquid part) for testing. The test may use immunoassay methods to detect specific antibodies against various allergens, including common triggers like pollen, dust mites, pet dander, or certain foods.

What Are Common Allergens Tested?

This screening typically includes a mix of common environmental and food allergens, such as house dust mites, grass pollen, tree pollen, cat/dog dander, mold spores, peanut, milk, egg, soy, and wheat. The exact mix may vary by lab, so ask your doctor which allergens are included in your specific test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Ig Mix Screen

Frequently asked questions

This test helps identify whether your immune system is producing antibodies against specific allergens, which can confirm or support a suspected allergy diagnosis. Elevated IgE levels to certain allergens may indicate an allergic reaction risk, while IgG antibodies can suggest past exposure or immune tolerance. Results guide treatment decisions, such as avoiding triggers or planning allergy immunotherapy.
How long will it take to get my results?
Results are usually available within 1–3 business days, depending on your lab and testing methods. Your doctor will discuss the findings with you during a follow-up visit.
What if my test results are positive for allergens I don’t recognize?
Do I need to do anything special before the test?
No special preparation is needed, but avoid taking antihistamines (like Benadryl) 24–48 hours before testing, as they may affect IgE antibody detection. If you’re on long-term allergy medications, check with your doctor first.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy