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Octanoylcarnitine (C8-Carnitine) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of octanoylcarnitine, a type of carnitine linked to fatty acid metabolism, in your blood.

Quick summary

["Octanoylcarnitine helps assess how well your body breaks down fats for energy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88014-6
Short code
Octanoylcarn/C0 DBS-sRto
Synonyms
Octanoylcarn/C0 DBS-sRto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Octanoylcarnitine?

Carnitines are compounds that help transport fatty acids into your mitochondria, where they’re used for energy. Octanoylcarnitine is one of several carnitine forms detected in blood tests. Elevated levels may indicate impaired fatty acid metabolism, while lower levels could suggest genetic or metabolic disorders affecting carnitine recycling.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like muscle weakness, fatigue, or unexplained metabolic issues. It’s also used in diagnosing conditions like medium-chain acyl-CoA dehydrogenase (MCAD) deficiency or other inherited metabolic disorders. Sometimes, it’s part of a broader evaluation for unexplained liver, kidney, or heart problems.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then processed in a lab to measure octanoylcarnitine levels using a specialized technique, often high-performance liquid chromatography (HPLC). Results are compared to reference ranges specific to your age and health status.

What Do Results Mean?

Interpreting results requires medical expertise. Elevated octanoylcarnitine may signal metabolic imbalances, while very low levels could indicate carnitine deficiency or genetic disorders. Your doctor will discuss findings in the context of your symptoms and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Octanoylcarnitine plays a critical role in fatty acid metabolism. Abnormal levels can signal underlying metabolic disorders, such as carnitine palmitoyltransferase (CPT) deficiencies, which impair energy production. Early detection can guide targeted treatments, including dietary adjustments or carnitine supplements.

Short name

C8 Carnitine

Frequently asked questions

What causes abnormal octanoylcarnitine levels?
Abnormal levels may result from genetic disorders affecting carnitine metabolism (e.g., MCAD deficiency), liver or kidney disease, severe infections, or certain medications. Unexplained high or low levels should be reviewed by your healthcare provider.
How soon will I receive my results?
Results typically arrive within 1–3 business days, depending on lab processing times. Your doctor will contact you to discuss findings and next steps, often within a few days of receiving the report.
Can diet or exercise affect octanoylcarnitine levels?
Yes, diet—especially high-fat or high-protein meals—can temporarily influence carnitine metabolism. Exercise may also affect levels, but results are usually interpreted in the context of your overall health and symptoms, not just a single test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy