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: Octanoylcarnitine (C8) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

: This test measures octanoylcarnitine, a medium-chain acylcarnitine, in serum or plasma, typically as part of a panel that screens for inherited fatty acid oxidation disorders.

Quick summary

[": Octanoylcarnitine is a marker used mainly to help detect rare metabolic conditions affecting how the body breaks down fats for energy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88006-2
Short code
Octanoylcarn/C0 SerPl-sRto
Synonyms
Octanoylcarn/C0 SerPl-sRto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Octanoylcarnitine?

: Octanoylcarnitine, sometimes called C8 acylcarnitine, is a compound formed when a medium-chain fatty acid (octanoic acid) binds to carnitine. Carnitine helps transport fatty acids into mitochondria, the energy-producing parts of cells, so this measurement reflects part of the body's fat-processing machinery.

: Why the Test Is Ordered

: The test is usually part of a broader acylcarnitine profile, often ordered during newborn screening or when a clinician suspects a fatty acid oxidation disorder. It can also help monitor patients known to have certain metabolic conditions. Results are interpreted together with other acylcarnitines and clinical findings.

: How the Sample Is Collected

: A blood sample is drawn from a vein into a collection tube, and serum or plasma is separated for analysis. The specimen is typically analyzed by a mass-spectrometry-based method. No special preparation is usually required unless your care team gives specific instructions.

: Understanding the Results

: A single octanoylcarnitine value is not interpreted on its own; reference ranges vary by laboratory, age, and method. Because the abbreviation for the analytical method in this slug is not clearly specified, this description stays general. Your clinician will compare your result with the laboratory's range and with other test findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Clinically, elevated octanoylcarnitine can be associated with disorders of medium-chain fatty acid oxidation, such as medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, but results must be confirmed with additional testing and clinical evaluation. Normal or mildly altered values can occur for many reasons, so this measurement is one piece of a larger diagnostic picture.

Short name

: C8 Acylcarnitine

Frequently asked questions

: Does an abnormal octanoylcarnitine result mean I have a metabolic disorder?
: Not necessarily. Abnormal results can occur with several conditions or technical factors, and they are usually followed up with repeat testing and additional metabolic tests before any diagnosis is made.
: Do I need to fast before this test?
: Fasting requirements depend on the specific panel and your care team's instructions. Follow the preparation guidance provided by your clinician or laboratory.
: Can medicines or diet affect the result?
: Yes, certain medications, supplements, and dietary factors can influence acylcarnitine levels. Tell your clinician about everything you take and follow any preparation instructions you are given.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy