Skip to content

Red Blood Cell Mass Concentration (Serum or Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the total mass of red blood cells present in a sample of your blood or body fluid.

Quick summary

["Understanding your red blood cell mass can help assess overall blood health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
34964-7
Short code
OF RBC-Imp
Synonyms
OF RBC-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test quantifies the combined weight of red blood cells (RBCs) in a given volume of your blood or fluid sample. RBCs carry oxygen throughout your body, and their mass concentration can reflect their overall quantity and potential health status.

Why Might You Need This Test?

Your healthcare provider may order this test if they suspect conditions affecting RBC production, distribution, or function, such as anemia, polycythemia, or other blood disorders. It may also be used in research or specialized clinical scenarios where precise RBC mass assessment is critical.

Common Uses and Contexts

This test is less commonly performed in routine clinical settings compared to standard RBC counts. It may be used in advanced diagnostic workflows, such as evaluating complex hematologic conditions, monitoring chronic diseases, or conducting specialized studies on blood components.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. If this test is performed on other fluids (e.g., plasma or cerebrospinal fluid), the sample type will be specified by your provider. Proper handling and storage of the sample are essential to ensure accurate results.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

RBC Mass Concentration

Frequently asked questions

How Might This Test Result Affect My Care?
A result may indicate abnormal RBC mass if it deviates significantly from expected levels, suggesting conditions like severe anemia (low RBC mass) or polycythemia (high RBC mass). Your healthcare provider will interpret results in the context of your medical history and symptoms to guide further evaluation or treatment.
FAQ Question 1
Is this test the same as a standard RBC count? No. While both assess RBCs, this test specifically measures their mass concentration rather than individual cell counts or other RBC-related metrics.
Your provider will discuss the result with you and may recommend additional tests or treatments based on the findings. Follow their guidance closely to address any underlying health concerns.
What should I do if my RBC mass test result is abnormal?
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy