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Serum or plasma mass concentration of lysine

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysine, an essential amino acid, in your blood. Lysine helps with protein synthesis, immune function, and calcium absorption.

Quick summary

["Lysine levels can help assess nutritional status or metabolic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13400-7
Short code
OH-Lysine Amn-mCnc
Synonyms
OH-Lysine Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Is Lysine?

Lysine is one of the nine essential amino acids your body cannot produce on its own. It plays key roles in maintaining muscle mass, supporting the immune system, and aiding calcium metabolism. While lysine is found in many foods, this test measures its concentration in your bloodstream.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of lysine deficiency (rare) or if you’re undergoing treatment that could affect amino acid levels, such as certain medications or dietary restrictions. It may also be part of broader metabolic or nutritional evaluations.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. The sample is sent to a lab for processing, where it is analyzed for lysine content. Results are reported as mass concentration (e.g., micrograms per milliliter).

What Does the Test Result Mean?

Interpretation depends on clinical context, not just a single value. Abnormal results may signal underlying conditions like malnutrition, certain metabolic disorders, or drug interactions. Your doctor will discuss findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lysine level

Frequently asked questions

How common is an abnormal lysine level?
Lysine deficiency is rare in healthy individuals with adequate protein intake. However, very low levels may indicate severe malnutrition, chronic illness, or conditions affecting amino acid metabolism. High levels could suggest liver disease or certain genetic disorders.
Can diet affect lysine test results?
Yes. High-protein diets (e.g., meat, dairy) may temporarily raise lysine levels. Avoiding certain foods or medications 24 hours before testing can help ensure accurate results.
What symptoms might trigger this test?
Symptoms like muscle weakness, frequent infections, or bone-related issues (e.g., osteoporosis) may prompt further metabolic testing, including lysine levels, especially if dietary history or medications are involved.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy